Sema4.ai Launches Enterprise Edition: Industry’s First ‘SAFE’ Enterprise AI Agent Platform

• The Sema4.ai Enterprise Edition is a trusted agentic platform that empowers businesses to build and deploy ‘SAFE” enterprise AI agents to execute data-driven knowledge work at scale.
  
  
• The new release of the Sema4.ai Enterprise Edition makes building and deploying AI agents faster and easier than ever before, including the introduction of Sai, an AI-powered Runbook builder.
  
  
• Sema4.ai Enterprise Edition delivers on the promise of enterprise AI agents by complying with the industry’s highest security and compliance standards including ISO 27001, SOC 2, and HIPAA.

ATLANTA, GA (April 16th, 2025)—Sema4.ai, the trusted enterprise AI agent company, today unveiled a new version of its Enterprise Edition— including its agentic platform SAFE (secure, accurate, fast, and explainable) designed for building, deploying, and managing AI agents at scale.

The latest release of the platform introduces Sai, a new AI-powered guide that simplifies the process of creating AI agents and Actions, making it faster and easier than ever. With Sai, business users—beyond just developers—can now build robust AI agents at enterprise scale. Enterprise Edition also includes enhanced security and governance certifications, positioning Sema4.ai as the preferred choice for large enterprises and Independent Software Vendors.

Get started today here.

Overcoming AI Adoption Barriers with the SAFE Construct

Despite significant investment in AI, most enterprises struggle to scale beyond pilot projects. In fact, BCG shows that only 4% of companies have successfully deployed AI at scale to drive real impact. Organizational challenges are many - from fragmented AI adoption, legacy system constraints, talent shortages, and governance concerns - preventing them from fully leveraging AI’s potential.

To address these barriers, Sema4.ai uses the SAFE construct for enterprise AI agents, which stands for:

• S ecure and governed: Ensuring robust security and governance practices are in place to protect sensitive data and maintain compliance across various industries.
  
  
• A ccurate and efficient: Delivering AI agents that operate with high precision while maximizing resource efficiency.
  
  
• F ast and easy: Enabling fast development and deployment, making it simple for organizations to integrate AI into their operations.
  
  
• E xplainable and predictable: Focusing on transparency, ensuring that AI agents’ actions and decisions are understandable and their outcomes are reliable.
  
  

Robust Security and Governance

Security and governance are key pillars of the SAFE construct. The Enterprise Edition incorporates robust security practices, meeting industry standards with certifications such as ISO 27001 (information security management), SOC 2 (security compliance), HIPAA (healthcare data protection), and GDPR (data privacy). The Sema4.ai Control Room enhances this by providing enterprise-grade security, scalability, and comprehensive lifecycle management for AI agents. These features ensure compliance today and lay the groundwork for future improvements, such as zero-copy data access, which helps reduce risk and improve performance.

Meet Sai: Build Better AI Agents, Faster

In the new Sema4.ai Enterprise Edition, Sai plays a critical role in enabling organizations to build, deploy, and manage AI agents with ease. Using the Sema4.ai Studio, Sai automatically generates natural language runbooks that capture business processes’ intent, output, and logic, enabling users to manage and refine workflows. Additionally, Sai recommends Actions for integrating AI agents with a wide range of enterprise applications, helping streamline workflows across the organization.

“Sai is designed for both business users and developers,” said Rob Bearden, CEO of Sema4.ai. “Sai supports you at every step, from defining agent tasks to integrating enterprise systems and optimizing workflows. By automating the development of both agents and actions that seamlessly integrate with your existing enterprise apps and leverage all data types, Sai eliminates complexity and speeds up the deployment of intelligent agents that do more than just simple tasks—they reason, collaborate, and take action, delivering real value across the organization.”

Building and deploying an AI Agent with Sai can be done in just a few steps:

1. Describe Your AI Agent in Plain English: First chat with Sai about what you need. Its easy-to-use chat interface asks key questions in English to define your agent’s purpose, tasks, and goals.

2. Generate a Fully Functional Runbook: Sai automatically turns your ideas into a Runbook—a structured guide that defines the AI agent’s logic, workflows, and decision-making. Previously written manually, Sai now generates it for you, saving time and effort.

3. Get Smart Action Recommendations: Once the Runbook is ready, Sai suggests Actions - these are the necessary integrations (e.g., Salesforce, Oracle, ERPs, CRMs, APIs) to ensure seamless enterprise connectivity.

4. Deploy and Monitor Performance: In the near future, Sai will also track AI agent performance, ensuring continuous improvement while maintaining compliance and security.

Ready to build and deploy AI agents at scale? Learn more about Sema4.ai’s trusted enterprise AI platform: here.


Read the SAFE Enterprise Edition blog: here.

About Sema4.ai
Sema4.ai is pioneering the future of knowledge work through trusted, enterprise-ready AI agents, the next generation of business applications that autonomously perform complex tasks with unprecedented accuracy and efficiency.

Founded by experts from Microsoft, AWS, VMWare, Cloudera, and Robocorp, Sema4.ai’s enterprise AI agents connect context to action, transforming collaboration between people and AI. Sema4.ai’s platform enables enterprises to seamlessly build, run, and manage AI agents that understand context, reason, act, and collaborate, forever changing how work gets done.

Sema4.ai believes enterprise AI agents are the “killer app” of the AI era—revolutionizing knowledge work, automating high-value tasks, and allowing employees to focus on strategic initiatives. The agents are designed to enhance human potential, driving operational efficiency, innovation, and significant cost savings for businesses worldwide. This is where the promise of AI meets the potential of people.

Contact Information

Eric Gonzalez

Media Contact

VSC for Sema4.ai

press@sema4.ai