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Exercise Can Combat High C-Reactive Protein Levels, Says Harvard Menís Health Watch


BOSTON, June 28 -- Inflammation anywhere in the body increases levels of a substance called C-reactive protein (CRP) in the blood. Many scientists suspect slightly elevated CRP levels are a hint that low-level inflammation may be fueling atherosclerosis and raising the risk for a heart attack, reports the July issue of Harvard Menís Health Watch.

ďRight now, we canít say for certain that lowering CRP will reduce heart attack risk, but there are clues that it might,Ē says Harvey Simon, M.D., editor of the Harvard Menís Health Watch. Statin therapy, moderate alcohol consumption, and low-dose aspirin are all associated with a reduced risk of coronary artery disease, and studies find that they also lower CRP levels. And this year, two major studies found that CRP levels predict risk even when cholesterol-lowering statins bring LDL cholesterol to very low levels.

Research suggests that exercise can also reduce CRP levels, says the Harvard Menís Health Watch. In one study, moderate exercisers were 15 percent less likely than couch potatoes to have elevated CRP levels, and those who exercised vigorously were 47 percent less likely to have a high CRP level. As of 2005, 12 additional studies have reported that people who exercise regularly have lower CRP levels than their sedentary counterparts.

Findings about CRP represent just one of many recent advances in understanding coronary artery disease. ďNew progress is soon to follow, but you should not wait for new results to take advantage of these insights,Ē says Dr. Simon. Regular exercise can reduce a manís risk for a host of ills, including cardiovascular disease, diabetes, an enlarged prostate, and erectile dysfunction. ďA brisk 30- to 40-minute walk nearly every day is enough exercise to yield important health benefits.Ē

Also in this issue:

-- Vitamin A and your bones

-- Meningitis vaccine

-- Diet, prostate cancer, and testicular cancer

-- Tape, medications, or both for knee pain

The Harvard Menís Health Watch is available from Harvard Health Publications, the publishing division of Harvard Medical School, for $24 per year. Subscribe at or by calling 1-877-649-9457 (toll free).

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