Wyeth Provides Regulatory Update Regarding Desvenlafaxine for the Treatment of Major Depressive Disorder

Company Underscores Commitment to Availability in Worldwide Markets

Collegeville, Pa. – Wyeth Pharmaceuticals, a division of Wyeth (NYSE:WYE), today provided an update on its global strategy for desvenlafaxine for the treatment of major depressive disorder (MDD) in adults.

Desvenlafaxine has already been approved for the treatment of MDD in adults in the United States, Australia and Brazil, and applications are currently pending in 22 markets. As part of its global regulatory strategy, and in consultation with the Committee for Medicinal Products for Human Use of the European Medicines Agency, the Company has chosen not to pursue its central European Marketing Authorisation Application at this time. Wyeth remains committed to making desvenlafaxine available to patients with MDD around the world, including in Europe. It is available in the United States under the name PRISTIQ.

“We are considering a number of options to support depressed patients and their families,” says Gary L. Stiles, M.D., Executive Vice President and Chief Medical Officer. “There are millions of patients with depression, and clearly more treatments are necessary.”

Wyeth has a long history of innovation in neuroscience. In 1993, the Company introduced the first serotonin-norepinephrine reuptake inhibitor, which has been prescribed to millions of people worldwide. Building on this research platform, desvenlafaxine represents Wyeth’s newest antidepressant therapy.