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Women’s health champion, Dr Riko Muranaka, awarded the 2017 John Maddox Prize for Standing up for Science


London  – WEBWIRE

Dr Riko Muranaka has been awarded the international 2017 John Maddox Prize1 for promoting science and evidence on a matter of public interest, despite facing difficulty and hostility in doing so. A journalist and lecturer at Kyoto University, Dr Muranaka is recognised for her work championing the use of evidence in public discussions of the Human Papilloma Virus (HPV) vaccine.

The HPV vaccine is recognised by the scientific and medical community, and endorsed by the World Health Organisation2 as key to preventing cervical and other cancers. In Japan the vaccine has been subject to a misinformation campaign to discredit its benefits, resulting in vaccination rates falling from 70% to less than 1%.

Dr Muranaka’s work to put the evidence for the safety of the vaccine clearly before the public has continued in the face of attempts to silence her with litigation and undermine her professional standing. In persisting, she has tried to ensure that a scientific account of the weight of evidence is available not only for Japanese families but for public health globally.

The John Maddox Prize, now in its sixth year, is a joint initiative of the leading international scientific journal Nature, the charity Sense about Science, supported by the Kohn Foundation, and is awarded to one or two people a year.

This year the prize received over 100 nominations from 25 countries4. The judges3 were struck not only by the diverse circumstances in which nominees persevered with communicating science – which may indicate growing recognition among the international research community of the value of engaging in society - but by the often extreme and unsupportive conditions in which some do this. In many of the examples this year, and in previous years, the judges found a lack of institutional support, and in some cases that the behaviour of researchers’ institutions contributed to the problems they faced in public discussion.

As a result, this year the judges have taken the unusual step of drawing attention to the challenges tackled by other nominees (see summary below) and calling for researchers’ employers, government agencies, funders and scientific organisations to consider what action they should be taking to ensure that researchers are properly supported and the public continue to have access to their discussions about evidence.

The prize was announced at 7pm GMT on 30 November at a reception in London.

Comments:

Accepting the prize Dr Muranaka said: “It is a great surprise and pleasure to be awarded such an honourable prize, one that commemorates a great editor and writer Sir John Maddox -- a champion of evidence who believed in promoting sound science in the public interest even in the face of hostility. In terms of my own work, I simply cannot ignore dangerous claims that threaten public health. I want people to hear the truth, that’s the reason I continue to write and speak out.”

Comments from the judges:

Sir Philip Campbell PhD, Editor-in-Chief, Nature“I congratulate Dr Muranaka on her achievements and for winning the award. In looking across the entries in this and in previous years, I would also like to emphasise the importance of institutions supporting their scientists who face hostility when standing up for evidence.”

Tracey Brown OBE, director, Sense about Science: “John’s insistence that we discuss the merits of research - publicly and without regard for fear or favour - could not have been more apparent in this year’s nominations. Our highly deserved winner Dr Muranaka has shown the courage and leadership that serves the public well but can put you in a lonely place. It is a place that too many science communicators will recognize and we all need to ask ourselves why that is and how to offer them greater solidarity.”

Colin Blakemore, professor of neuroscience and philosophy, School of Advanced Study, University of London: “Once again, the judges were so impressed by stories of the courage and resilience of scientists, medics and journalists who have struggled against prejudice and vested interests. Riko Muranaka stood out because of her long and determined efforts to inform the public, in Japan and the wider world, about the health benefits of HPV vaccination, despite vilification, litigation and threats to her professional standing.”

Lord (Martin) Rees of Ludlow OM FRS, University of Cambridge: “It is gratifying to see a more global encouragement of public engagement in research institutions, but these institutions need to shown serious thought on how to support researchers through their experiences at the rougher end of public debate, for example when investigating potentially vexatious complaints”.

Natasha Loder, The Economist“Speaking truth against vested interests has never been more important. But it is difficult and sometimes comes at great cost. This year, the judges of the John Maddox Prize felt compelled to commend the efforts of a number of entrants. Dr Muranaka’s bravery and strength in fighting for public health stood out among this year’s brilliant applicants. She is fighting to ensure that Japanese girls have access to the HPV vaccine in the face of a successful misinformation campaign.” 

Brenda Maddox, patron of the John Maddox Prize: “My late husband John had an unusual combination of knowledge of science and eloquence of expression. Someone once asked him, ‘how much of what you print is wrong?’ referring to Nature. John answered immediately, ‘all of it. That’s what science is about – new knowledge constantly arriving to correct the old.’”

Dr Katsuyuki Kinoshita, chairman of the Japanese Association of Obstetricians and Gynaecologists, and nominator of Dr Muranaka for the 2017 John Maddox Prize: “I heartily congratulate Dr Muranaka on her winning of the 2017 John Maddox Prize. Her courageous challenge in demonstrating the safety of the HPV vaccine, despite insult, litigation and attempts to undermine her professional status, epitomises the core spirit of the Maddox Prize. I believe this Prize will have a strong impact on the Ministry of Health, Labour and Welfare, in promoting the use of HPV vaccine in the Japanese society. Furthermore, I hope this award will help convince sceptical medical professionals and journalists of the great public benefit of this vaccine.”

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1. The John Maddox Prize for Standing up for Sciencein its sixth year, recognises the work of individuals anywhere in the world who promote sound science and evidence on a matter of public interest, facing difficulty or hostility in doing so. The winners receive a certificate and £2,000. Previous winners were: Professor Elizabeth Loftus (2016), Professor Edzard Ernst, Professor Susan Jebb (2015); Dr Emily Willingham, Dr David Robert Grimes (2014); Professor David Nutt (2013); Professor Sir Simon Wessely, Shi-min Fang (2012).

Candidates were judged on the strength of their nomination based on these criteria:

  • How clearly the individual communicated good science, despite adversity.
  • The nature of adversity faced by the individual.
  • How well they placed the evidence in the wider debate and engaged others.
  • Their level of influence on the public debate.

2. Meeting of the Global Advisory Committee on Vaccine Safety, 7–8 June 2017 “There are now accumulated safety studies that include several million persons and which compare the risks for a wide range of health outcomes in vaccinated and unvaccinated subjects. However, despite the extensive safety data available for this vaccine, attention has continued to focus on spurious case reports and unsubstantiated allegations. The Committee continues to express concern that the ongoing unsubstantiated allegations have a demonstrable negative impact on vaccine coverage in a growing number of countries, and that this will result in real harm.”

Human papilloma virus vaccines: WHO position paper, May 2017 “Two HPV vaccines are now being marketed in many countries throughout the world - a bivalent and a quadrivalent vaccine. Both vaccines are highly efficacious in preventing infection with virus types 16 and 18, which are together responsible for approximately 70% of cervical cancer cases globally. The vaccines are also highly efficacious in preventing precancerous cervical lesions caused by these virus types. Data from clinical trials and initial post-marketing surveillance conducted in several continents show both vaccines to be safe.”

3. The judging panel consisted of Professor Colin Blakemore FRS, Tracey Brown OBE (Sense about Science), Sir Philip Campbell PhD (Nature), Lord Rees of Ludlow OM FRS and Natasha Loder (the Economist). The judges sat in a personal capacity and the choice of the award does not indicate the view of any organisation they are associated with.

4. The 2017 John Maddox Prize received over 100 nominations for 95 individuals from 25 different countries. In 2016 there were 59 individuals from 17 countries, 50 in 2015 and 44 in 2014.

Sir John Maddox (1925-2009) was the editor of Nature from 1966 to 1973, and from 1980 until 1995, and laid the foundations for Nature as it is today, establishing a system of peer review and instituting a strong tradition of journalism. He was also a founding trustee of Sense about Science and the inspiration for many programmes of work including its now internationally established VoYS (Voice of Young Science) network.

This prize commemorates Sir John as a passionate and tireless communicator and defender of science. As a writer and editor at Nature for 22 years, he changed attitudes and perceptions, engaging with difficult debates and inspiring others to do the same.

Sir John, in the words of his friend and former Nature news editor Walter Gratzer: “wrote prodigiously on all that was new and exciting in scientific discovery and technological advance, denouncing fearlessly what he believed to be wrong, dishonest or shoddy. He did it with humour and grace, but he never sidestepped controversy, which he seemed in fact to relish. His forthrightness brought him some enemies, often in high places, but many more friends. He changed attitudes and perceptions, and strove throughout his long working life for a better public understanding and appreciation of science.”


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