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Galapagos achieves milestone in osteoporosis collaboration with Lilly


Mechelen, Belgium - Galapagos NV (Euronext: GLPG) announced today that it has reached a milestone in its osteoporosis collaboration with Eli Lilly and Company (NYSE:LLY), triggering a payment of €2.5 million from Lilly.

In December 2007, Lilly and Galapagos initiated an alliance to develop new medicines for the treatment of osteoporosis. The agreement provides Lilly access to 12 of Galapagos’ novel target based programs in osteoporosis, with Galapagos responsible for the development of drug candidates through to Phase IIa clinical Proof of Concept. The milestone announced today is the result of one of these programs reaching the next phase of medicinal chemistry optimization. To date, Galapagos has received a total of €3.9 million in milestone payments from Lilly under the alliance.

“We remain on-track in the osteoporosis alliance with Lilly,” said Onno van de Stolpe, Galapagos’ CEO. “Through milestone payments such as the one announced today, we are able to finance the progression of multiple osteoporosis drug candidates toward the clinic.”

About osteoporosis
Osteoporosis is principally an age-related disease, when hormone levels essential for maintaining bone density decline. The development of osteoporosis is characterized by a clinically significant reduction in bone density. The disease is four times as common in women as men. The enormous health care costs associated with osteoporosis, estimated at $15 billion per year in the USA alone, are related to the greatly increased incidence of fractures in osteoporosis patients.

About Galapagos
Galapagos (Euronext: GLPG; OTC: GLPYY) is a drug discovery and development company with small molecule programs in bone and joint diseases, bone metastasis, cachexia, anti-infectives and metabolic diseases. It has established risk sharing alliances with GSK, Janssen Pharmaceutica, Eli Lilly and Merck. Through an alliance with MorphoSys, Galapagos is also developing new antibody therapies in bone and joint diseases. Its division BioFocus DPI offers a full suite of target-to-drug discovery products and services to pharmaceutical and biotech companies and to patient foundations, encompassing target discovery and validation, screening and drug discovery through to delivery of pre-clinical candidates. Galapagos currently employs 490 people and operates facilities in six countries, with global headquarters in Mechelen, Belgium. More info at:

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