BASF launches Kollidon® VA 64 Fine
* New binder helps to optimize customers’ production processes
* Production of tablets with increased hardness now possible
10/31/05, BASF will present a new binder for tablet production, Kollidon® VA 64 Fine, at the pharmaceutical industry’s most important tradeshow, the Convention on Pharmaceutical Ingredients (CPhI), which will be held in Madrid/Spain from November 1-3, 2005. The new product is a further refinement of Kollidon® VA 64 with a smaller particle size.
“Our goal was to design an excipient that can be used for both direct compression and roller compaction,” says Dr. Tim Bölke, Director Strategic Marketing, Pharma Solutions. Kollidon® VA 64 Fine now makes this possible, allowing manufacturers to reduce production process times for solid oral dosage forms. “This optimizes the entire production process and helps our customers to save costs,” Bölke explains.
The significantly smaller particle size of Kollidon® VA 64 Fine increases the tensile strength of the tablet cores and makes them less susceptible to breakage and abrasion. Increased stability results in easier tablet handling and improved protection during transport.
In August 2005, the polymer copovidone, on which Kollidon® VA 64 and Kollidon® VA 64 Fine are based, was granted “generally recognized as safe/self-affirmed” (GRAS/SA) status by the U.S. health authorities (FDA). Following this approval, BASF customers are now also able to use these polymers in dietary supplements and other food products intended for the U.S. market.
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