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Thomson Pharma Chemical Structures Now Indexed In PubChem Database From US National Institutes Of Health


Additional 2.2 Million Structures Now Searchable
in Freely Available Database

Philadelphia, PA USA, London UK 11/06/2006, Thomson Scientific, part of The Thomson Corporation (NYSE: TOC; TSX: TOC) and leading provider of information solutions to the worldwide research and business communities, today announced the deposit of 2.2 million chemical structures from Thomson Pharma into PubChem, the freely accessible database that provides information on the biological activities of small molecules. PubChem was developed by the National Center for Biotechnology Information at the US National Institutes of Health (NIH) to help biomedical researchers identify chemical structures with the potential to treat diseases. The addition of Thomson Pharma’s extensive collection of biologically active and pharmacologically active structures, derived from worldwide patent and literature sources, significantly enhances the value of this research tool to the scientific and medical community.

Thomson Pharma ( is the comprehensive pharmaceutical information solution that covers the entire drug discovery and development pipeline. PubChem searchers with a Thomson Pharma subscription can link directly from PubChem to more detailed information on their structure of interest including:

• activities reported for that compound
• drug reports citing that compound
• synthetic methods and critical reaction data
• patents, journals and news stories that feature the compound
• synonyms and trade names
• related salts and isomers

“My colleagues and I are very pleased to welcome the addition of Thomson Pharma chemical structures to PubChem,” said Steve Bryant, Director, PubChem, National Institutes of Health. “This will allow our users to cross-reference information in PubChem, such as biological testing results from the NIH Molecular Libraries program, with the further rich sources of information provided by Thomson Pharma.”

“We are pleased to partner with the NIH to give PubChem searchers access to Thomson Pharma’s extensive collection of chemical structures,” said Jon Brett Harris, executive vice president of Pharmaceutical and Chemical Markets at Thomson Scientific. “We look forward to building on this collaboration to further enhance the value of PubChem for researchers in commercial, academic and government organizations worldwide.”

About NIH
The National Institutes of Health (NIH)-The Nation’s Medical Research Agency-includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. It is the primary Federal agency for conducting and supporting basic, clinical and translational medical research, and it investigates the causes, treatments and cures for both common and rare diseases. The PubChem database, a component of NIH’s Molecular Libraries Roadmap Initiative, is a comprehensive database of chemical structures and their biological activities being developed by the National Center for Biotechnology Information (NCBI), a division of the National Library of Medicine at NIH. For more information about NIH and its programs, visit

About The Thomson Corporation
The Thomson Corporation (, with 2005 revenues of approximately $8.40 billion, is a global leader in providing integrated information solutions to business and professional customers. Thomson provides value-added information, software tools and applications to more than 20 million users in the fields of law, tax, accounting, financial services, higher education, reference information, corporate e-learning and assessment, scientific research and healthcare. With operational headquarters in Stamford, Conn., Thomson has approximately 40,500 employees and provides services in approximately 130 countries. The Corporation’s common shares are listed on the New York and Toronto stock exchanges (NYSE: TOC; TSX: TOC).

Thomson Scientific is a business of The Thomson Corporation. Its information solutions assist professionals at every stage of research and development—from discovery to analysis to product development and distribution. Thomson scientific information solutions can be found at


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