Evotec Extends and Broadens Research Agreement with Cubist Pharmaceuticals
Collaboration expanded to include integrated fragment-based drug discovery activities on additional antibacterial targets
Hamburg, Germany - Evotec AG (Frankfurt Stock Exchange: EVT, TecDAX) today announced that it has extended its research agreement with Cubist Pharmaceuticals, Inc. (NASDAQ: CBST) to the end of 2010. Under the contract extension, Evotec will provide additional fragment-based drug discovery expertise using its proprietary platform, EVOlutionTM, which includes fragment screening, structural biology and protein crystallography, to discover and profile novel compounds against additional antibacterial targets selected by Cubist.
Evotec and Cubist have collaborated since July 2009, successfully progressing drug discovery programmes. Over the course of 2010, Evotec will continue and expand its support of Cubistís discovery activities. A key benefit of Evotecís fragment-based drug discovery platform is its versatility, combining biochemical and biophysical techniques including nuclear magnetic resonance (NMR), surface plasmon resonance (SPR) and x-ray crystallography, thus allowing the design of target-specific strategies.
Dr Mark Ashton, Executive Vice President, Business Development of Evotec commented: ďThis is further validation of our expertise and capabilities in fragment-based drug discovery. We enjoy the close and productive relationship we have with Cubistís scientists and look forward to carry on adding significant value to their portfolio of antibacterial programmes.Ē
No financial details are disclosed.
EVOlutionTM is Evotecís fragment-based drug discovery platform which combines biochemical and biophysical techniques including nuclear magnetic resonance (NMR), surface plasmon resonance (SPR) and x-ray crystallography for the screening of low molecular weight compounds and fragments. By the combination of the orthogonal screening technologies, Evotecís fragment screening platform is capable of screening a more diverse set of biological targets than other fragment screening approaches, as well as being able to screen the fragments in a high-throughput mode. The benefit of this is the ability to identify active fragments for numerous classes of biological targets in a short space of time. For further information, please see: www.evotec.com/fragment-based drug discovery.
About Fragment-based Drug Discovery
Fragment-based drug discovery (FBDD) is a new paradigm in drug discovery that utilises very small molecules - fragments of more complex molecules - to generate efficient starting points for drug discovery. This approach thus provides the opportunity to effectively manage the molecular weight and overall complexity of drug candidates, a recognised success factor in drug development.
Contact Evotec AG:
Dr Werner Lanthaler, Chief Executive Officer, Phone: +49.(0)40.56081-242, firstname.lastname@example.org
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